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Alexander de Leon

photograph of Alexander de Leon

Job Title:

  • Associate Professor

Phone:

  • +1 (403) 220-6782

Office:

  • MS 554

Email:

Web site:

Degrees:

Sabbatical Leave:

  • I am away on sabbatical during the period July 2009-June 2010.  I can be contacted by email.

Research Interests:

  • Methods for correlated data
  • Models for mixed discrete and continuous outcomes
  • Assessment of diagnostic tests
  • Statistical problems in medicine
  • Pseudo- and composite likelihood methods
  • Copula models

Masters Students:

  • Yifan Zhu
  • Beilei Wu (2009)
  • Yongtao (Bruce) Zhu (2006)
  • Meijie Guo (2005)

Honours & Awards:

  • NSERC - unclassified (2007 - 2012)

Past Courses:

  • STAT213 - Introduction To Statistics I
  • STAT217 - INTRODUCTION TO STATISTICS II
  • STAT407 - APPLIED PROBABILITY
  • STAT421 - MATHEMATICAL STATISTICS
  • STAT429 - APPLIED REGRESSION ANALYSIS
  • STAT525 - MULTIVARIATE ANALYSIS
  • STAT625 - Multivariate Analysis
Representative Publications:
Preprint
de Leon, Alexander, Soo, Andrea and Williamson, T. "Classification with discrete and continuous variables via general mixed-data models" Journal of Applied Statistics (to appear)
de Leon, Alexander and Wu, Beilei. "Copula-based regression models for a bivariate mixed discrete and continuous outcome" (2009)
Book Chapter
de Leon, Alexander and Carriere Chough, K. Mixed-outcome data In Encyclopedia of Biopharmaceutical Statistics. Ed. Shein-Chung Chow. Informa Healthcare (2009): To appear.
Journal Paper
de Leon, Alexander, Soo, A, Bonzo, D and Rudnisky, C. "Joint estimation of diagnostic accuracy measures for paired organs-Application in ophthalmology" Biometrical Journal 51.5 (2009): 837-850
de Leon, Alexander and Zhu, Y. "ANOVA extensions for mixed discrete and continuous data" Computational Statistics & Data Analysis 52.4 (2008): 2218-2227
de Leon, Alexander, Guo, M, Rudnisky, CJ and Singh, G. "A likelihood approach to estimating sensitivity and specificity for binocular diagnostic data: Application in ophthalmology" Statistics in Medicine 26.17 (2007): 3300-3314
de Leon, Alexander and Carriere, KC. "General mixed-data model: Extension of general location and grouped continuous models" Canadian Journal of Statistics 35.4 (2007): 533-548
de Leon, Alexander. "One-sample likelihood ratio tests for mixed data" Communications in Statistics. A. Theory and Methods 36.1 (2007): 129-141
Rudnisky, CJ, Tennant, M, de Leon, Alexander, Hinz, B and Greve, M. "Benefits of stereopsis when identifying clinically significant macular edema via teleophthalmology" Canadian Journal of Ophthalmology 41.6 (2006): 727-732
Somani, R, Tennant, M, Rudnisky, CJ, Weis, E, Ting, A, Greve, M, Hinz, B and de Leon, Alexander. "Comparison of stereoscopic digital imaging to film in the identification of macular degeneration" Canadian Journal of Ophthalmology 40.3 (2005): 293-302
de Leon, Alexander. "A generalized Mahalanobis distance for mixed data" Journal of Multivariate Analysis 92.1 (2005): 174-185
de Leon, Alexander. "Pairwise likelihood approach to grouped continuous model and its extension" Statistics and Probability Letters 75.1 (2005): 49-57
Baker, C, Rudnisky, CJ, Tennant, M, Sanghera, P, Hinz, B, de Leon, Alexander and Greve, M. "JPEG compression of stereoscopic digital images for diagnosis of diabetic retinopathy via tele-ophthalmology" Canadian Journal of Ophthalmology 39.7 (2004): 746-754
Rudnisky, CJ, Hinz, B, Tennant, M, de Leon, Alexander and Greve, M. "High-resolution stereoscopic digital fundus photography versus contact-lens biomicroscopy for the detection of clinically significant macular edema" Ophthalmology 109.2 (2002): 267-274
de Leon, Alexander and Carriere, KC. "On the one-sample location hypothesis for mixed bivariate data" Communications in Statistics. A. Theory and Methods 29.11 (2000): 2573-2581

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